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MA, USA); and O-Phenylenediamine dihydrochloride and bovine serum albumin were purchased from sigma aldrich (st. louis, MO, USA). MaxiSorp flat-bottom 96-well plates were purchased from Nunc GmbH & Co.

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3 Division of Immunology, Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA. 4 molecular biology section, Division of Biological Sciences, Department of Cellular.

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